A novel peptide to enhance recombinant BMP-2 production in mammalian cell cultures
نویسندگان
چکیده
منابع مشابه
A novel peptide to enhance recombinant BMP-2 production in mammalian cell cultures
Background Due to their osteoinductive properties, recombinant human bone morphogenetic proteins (rhBMPs) have been used successfully for bone regeneration and replacement. However, the yields rhBMPs yields in mammalian expression systems are very low, resulting in their high cost. BMPs are synthesized as a precursor, proBMP, which undergoes enzymatic cleavage by proprotein convertases (PCs) to...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2011
ISSN: 1753-6561
DOI: 10.1186/1753-6561-5-s8-p96